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The process of assigning workload to nurses is significant in promoting high nursing retention rates, and positive patient outcomes. The concept, workload is widely used but there is no clear delineation of the concept as it relates to nursing. The aim of this analysis was to explore the concept of workload, as it relates to nursing using the Walker and Avant method. The analysis revealed: a) three attributes (time, mental state, and assignment); b) four antecedents (health, environment, nursing, and person); c) and three consequences (safety of practice, retention rate and cost). It is essential that nursing leaders create and use a systematic approach to guide the staffing process to create a balance workload. As a result, nursing practice will be safer and optimal patient outcomes will be achieved.